Since the 2017 season, Louisville and Virginia Tech have met 9 times, and Virginia Tech has the better of it at 6–3.
Most recently Virginia Tech won 11–4 on March 23, 2025.
Right now Louisville is 30–27 and Virginia Tech is 30–26, with Louisville at 156 days since a win against Virginia Tech's 152.
| Date | Site | Winner | Score |
|---|---|---|---|
| Sun, Mar 23 2025 | Virginia Tech home | Virginia Tech | 11–4 |
| Sat, Mar 22 2025 | Virginia Tech home | Louisville | 12–8 |
| Fri, Mar 21 2025 | Virginia Tech home | Virginia Tech | 5–4 |
| Sun, Mar 17 2024 | Louisville home | Virginia Tech | 8–1 |
| Sat, Mar 16 2024 | Louisville home | Virginia Tech | 12–6 |
| Fri, Mar 15 2024 | Louisville home | Louisville | 9–6 |
| Sun, May 15 2022 | Virginia Tech home | Virginia Tech | 6–4 |
| Sat, May 14 2022 | Virginia Tech home | Virginia Tech | 4–3 |
| Fri, May 13 2022 | Virginia Tech home | Louisville | 8–1 |
Full schedules and drought counters: Louisville Cardinals and Virginia Tech Hokies.
Louisville vs Boston College, Louisville vs California, Louisville vs Clemson, Louisville vs Duke, Louisville vs Florida State, Louisville vs Georgia Tech, Louisville vs Miami, Louisville vs NC State, Louisville vs North Carolina, Louisville vs Notre Dame, Louisville vs Pittsburgh, Louisville vs Stanford, Louisville vs Virginia, Louisville vs Wake Forest.
Virginia Tech vs Boston College, Virginia Tech vs California, Virginia Tech vs Clemson, Virginia Tech vs Duke, Virginia Tech vs Florida State, Virginia Tech vs Georgia Tech, Virginia Tech vs Miami, Virginia Tech vs NC State, Virginia Tech vs North Carolina, Virginia Tech vs Notre Dame, Virginia Tech vs Pittsburgh, Virginia Tech vs Stanford, Virginia Tech vs Virginia, Virginia Tech vs Wake Forest.