Since the 2017 season, Louisville and Virginia Tech have met 20 times, and Virginia Tech has the better of it at 15–5.
Most recently Virginia Tech won 12–5 on March 16, 2025.
Right now Louisville is 44–14 and Virginia Tech is 48–12, with Louisville at 166 days since a win against Virginia Tech's 156.
| Date | Site | Winner | Score |
|---|---|---|---|
| Sun, Mar 16 2025 | Louisville home | Virginia Tech | 12–5 |
| Fri, Mar 14 2025 | Louisville home | Virginia Tech | 5–2 |
| Fri, Mar 14 2025 | Louisville home | Virginia Tech | 10–0 |
| Sun, Mar 10 2024 | Louisville home | Virginia Tech | 4–3 |
| Sat, Mar 9 2024 | Louisville home | Virginia Tech | 5–2 |
| Sat, Mar 9 2024 | Louisville home | Virginia Tech | 11–1 |
| Thu, May 11 2023 | Louisville home | Virginia Tech | 10–8 |
| Sun, Apr 24 2022 | Virginia Tech home | Virginia Tech | 7–4 |
| Sat, Apr 23 2022 | Virginia Tech home | Virginia Tech | 3–0 |
| Fri, Apr 22 2022 | Virginia Tech home | Virginia Tech | 4–3 |
| Sun, Mar 28 2021 | Louisville home | Virginia Tech | 8–0 |
| Sat, Mar 27 2021 | Louisville home | Louisville | 3–2 |
| Sat, Mar 27 2021 | Louisville home | Virginia Tech | 2–0 |
| Fri, Mar 26 2021 | Louisville home | Virginia Tech | 3–0 |
| Sun, Mar 31 2019 | Virginia Tech home | Virginia Tech | 13–5 |
| Sat, Mar 30 2019 | Virginia Tech home | Virginia Tech | 10–1 |
| Fri, Mar 29 2019 | Virginia Tech home | Louisville | 7–5 |
| Sat, Apr 15 2017 | Virginia Tech home | Louisville | 10–8 |
| Fri, Apr 14 2017 | Virginia Tech home | Louisville | 6–0 |
| Fri, Apr 14 2017 | Virginia Tech home | Louisville | 13–6 |
Full schedules and drought counters: Louisville Cardinals and Virginia Tech Hokies.
Louisville vs Boston College, Louisville vs California, Louisville vs Clemson, Louisville vs Duke, Louisville vs Florida State, Louisville vs Georgia Tech, Louisville vs NC State, Louisville vs North Carolina, Louisville vs Notre Dame, Louisville vs Pittsburgh, Louisville vs Stanford, Louisville vs Syracuse, Louisville vs Virginia.
Virginia Tech vs Boston College, Virginia Tech vs California, Virginia Tech vs Clemson, Virginia Tech vs Duke, Virginia Tech vs Florida State, Virginia Tech vs Georgia Tech, Virginia Tech vs NC State, Virginia Tech vs North Carolina, Virginia Tech vs Notre Dame, Virginia Tech vs Pittsburgh, Virginia Tech vs Stanford, Virginia Tech vs Syracuse, Virginia Tech vs Virginia.